Responsibilities for Scientific Studies and Research Funded by Public or Private Institutions

Competitively Funded Projects
  • Principal Investigator (PI) of “Ovarian Reserve in Women and Their Reproductive Performance,” GR-2009-1580036, funded in 2009 (three-year duration) by the Italian Ministry of Health on a competitive, peer-reviewed basis.
  • FORWARD Grant 2020 – PI of “Desogestrel versus GnRH Antagonist (Ganirelix) in IVF/ICSI Patients Undergoing Ovarian Stimulation (DEGOS),” awarded competitively in 2020.
  • COVID-19 Grant – PI of “Placental Expression of SARS-CoV-2 Receptors: Implications in COVID-19 Vertical Transmission,” competitively awarded in May 2020. 
Projects Funded by Private Sponsors (Phase 3 and 4 Clinical Trials)
  • PI – ESTHER 1: Efficacy and safety of FE999049 combined with follitropin alfa (GONAL-F) in controlled ovarian stimulation for women undergoing assisted reproductive technology programs.
  • PI – ESTHER 2: Immunogenicity of FE999049 in repeated controlled ovarian stimulation cycles in women undergoing ART programs.
  • PI – LIBERTY Trial: Multicenter international trial with investigational drug Relugolix.
  • PI – SPIRIT Trial: Multicenter international trial with investigational drug Relugolix.
  • PI – SOFIA Study: Safety of Ovaleap (follitropin alfa) in infertile women undergoing superovulation for ART. An international, prospective, observational, comparative cohort study.
Investigator Initiated Studies (IISs)
  • PI: In vitro study on the effects of human menopausal gonadotropin (HMG) versus recombinant human FSH (r-FSH) on gene expression in primary human granulosa cell cultures.
  • PI: Evaluation of the effect of ulipristal acetate on ovarian reserve parameters in infertile women with intramural uterine fibroids scheduled for surgery.
  • PI: Effects of corifollitropin alfa compared with r-hFSH in cultured human granulosa cells.
  • PI: Studies on recombinant FSH (follicle-stimulating hormone) products.
  • PI: Investigation of the cellular functions of Anti-Müllerian Hormone (AMH).
  • PI: Project on HCG and FSH effects on endometrial cell survival and implantation-related gene expression.
  • PI: Personalization of FSH dosing in IVF/ICSI cycles.
  • PI: AMH Nomogram Study: a cohort study on diagnostic methodology.
  • PI: Use of progestins versus GnRH analogs to inhibit spontaneous ovulation in IVF cycles – a potential new era.
  • PI: Laboratory variability in AMH measurement according to automated assay systems.
  • PI: Observational single-center study investigating the relationship between serum AMH dynamics and early or normal ovarian response to corifollitropin alfa (ACO Study).
Team Led by Prof. Giovanni Grandi
  • Co-PI of “Assisted Reproductive Technology (ART) and Pregnancy Outcomes in Women with Adenomyosis (Internal Endometriosis) According to Stimulation Protocol in Relation to Immunological and Endometrial Characteristics: A Prospective, Randomized Study” (PI: Prof. Fabio Facchinetti), funded with €415,724.67 by the Ministry of Health Endometriosis Research Call, approved under CE AVEN Protocol AOU 0035151/22, 05/12/2022. PI of this project from 11/01/2023.
  • Co-PI of PRIN 2022 project “Precocious Biomarkers of Unilateral Uretero-Pelvic Junction Obstruction in Children – The PRO-FUTURE Project” (PI: Dr. P. Marzuillo), funded with €250,000.
  • Co-PI of Unit 3 of the project “Genitourinary Syndrome in Breast Cancer Patients: The Common Untold Unmet Need,” funded by the Emilia-Romagna Finalized Health Research Program (FIN-RER) 2020, €142,000.
  • Winner of the Junior Grant: “Development of a Vaginal Ring for the Simultaneous Administration…: CO-RING Project,” Department of Medical and Surgical Sciences Maternal-Child and Adult, UNIMORE, Departmental FAR Call, starting 12/01/2023 (PI: Dr. Martina Arabia).
Patents
  • Inventor of patent “Device for Intravaginal Administration of Bacteria and Their Metabolites,” University of Modena and Reggio Emilia, 2025, number P11016IT00.